Personally, my choice is St. John's Wort. It works for me. And generally doesn't make me tired, although especially when I first started, if I took it with chamomile, valerian, or any other herbs that make you tired, it knocked me out. Now I start the day in the morning with St. John's Wort and Mate (should be an accent on the e), and that's just about right.

Prescription antidepressants that are noted for less or no sedation are Bupropion, Fluoxetine, Sertraline, Citalopram, Escitalopram. Venlafaxine and Duloxetine are also mild for sedation.