Let's hope this one will work for you. I've been seriously depressed, weak and tired on Effexor also, so my P-doc is having me go off of it. Now to find out what shall replace it. I suspect Lamictal. I think we all just want to feel better already! AHHHHHHHHH. I hate lying around all day and not caring about anything. At least I can come on here and have some semblance of a life. Feel better soon. Sorry for dumping.