Dear Lynnie,
I was on zyprexa for years, then because of side effects (weight gain, diabetes) they changed me to Seroquel last summer. Even tho it says it's for schizophrenics, it's also used to treat us BPs. The only problem(s) I found with it was that it makes me incredibly sleepy, I have to be very careful about the dose, I can only tolerate 300mg at the most, most days only take 150mg.
It also has the benefit of working as an antidepressant, so they took me off my Prozac. However, I was still having episodes of depression so was put back on my Prozac. It's probably because I can't take a "therapeutic" dose of the Seroquel. Anyway, I am still holding steady on it for use for the BP.
I wish you luck.