I think it's probably true for most of us. People who are around you the most often or calling you the most often can get on your nerves. I know my mom drives me into depression sometimes by telling me what's going on with her and the other members of my family. My mate can say or do the slightest thing when I'm already irritable and I explode at him. And he says, "Fine, I'll never say anything again." And I tell him that was an overreaction to my overreaction. And he's still huffing and I apologize and he says he'll leave me alone until I'm out of "this mood." So, I don't want to have an outburst at him, and yes I value my alone time, and don't feel like I get enough of it any more, but facts are we'll always have people in our lives, but who they are can fluctuate with time. You lose some friends, make others. Children grow up, couples drift apart, etc. You know all this. We could (if we really wanted to) be hermits in the mountains, or whatever, but for most of us it's impractical. We need a group of friends and we still need to buy food and socialize every once in a while. (I still figure I will be alone one day on a deserted Greek Island and freak out the daytrippers for my own amusement by making them think it's haunted. )

So, it's okay to get snippy every once in a while. Our family and friends do it to us on occasion too. If they love you; they will understand, especially if you're adjusting to new meds. You'll still feel bad about it and apologize and think things like "they'd be better off without me," but if that were true, they'd all have abandoned you by now. They need you as much as you need them.

And maybe you do need to take a vacation by yourself for a couple days or a week. Think about it. I find my alone time very restorative.