AH - I have seen many people use less Seroquel™ (quetiapine) at bedtime. For getting to sleep, I find that giving a large initial dose of Seroquel (or Zyprexa™ - olanzapine, etc) can be like hitting someone with a hammer; the large doses get you to sleep and keep you asleep, but when that interferes with daily function, the dose may be cut back (depending upon existing circumstances).

The Seroquel can cause the hangover effect that you are describing, especially when starting the drug. This does go away in most people, usually within the first month.

Ask your doc, you might get him/her to lower the dose to 50mg (or even 25mg) to allow you to build the dose gradually, which usually does reduce the tiredness as well.

- Sorry about the mix-up
- Cam