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I was on Seroquel several years ago and came off....I have had to restart since March. The Pdoc started me out at 300 mg since in the past I ended up on 800 mg...boy did I find out my body had changed !! 300 mg was too much this go around so we tried 200 down to 100 mg. Like most other drugs, after awhile the body does get sorta immune to the effects and the side effects aren't as drastic. My Pdoc now tells me to use a "sliding scale" of Seroquel to meet my needs....when I'm most manic, I find the 200 mg is what I need to get some sleep...when not as manic, the 100 mg works well enough. For me, after several month, I found the morning "hangover" lessened with consistant use of Seroquel and not skipping nights.
Hope this helps and good luck to you.
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Courage doesn't always ROAR....
Sometimes courage is the quiet voice at the end of the day saying...."I made it through today and I will try again tomorrow".
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