My pdoc has me on all three drugs. I started with 3 mg Xanax when I started therapy early in 2004. My T suggested it to my primary care doctor. Then a year later he suggested we adjust my antidepressant and I told him I was not taking anything. He got very concerned and had me make an appointment with a pdoc for the medication aspect of my treatment. The pdoc I chose also does some therapy with me and is friends with my T so I wrote out that they can share info about me. He prescribed 20 mg Lexapro every night. Then, last month, my pdoc started my on seroquel. This is the drug my mother took for schizophrenia just before she died. I read that it was also for bipolar and my pdoc once mentioned that I might be that as well as suffering from major depression and general anxiety. These drugs are supposed to make me sleep but they do not always seem to work that way. I do feel calmer but also detached from reality when taking them. Does anyone else take this combination?