Plenty of times I feel like I'm somehow out-of-the-loop that so many others seem to be in, although I think this applies to everyone. For people I know more of and socialize more with, I don't really have this although I suppose that's something to be expected. Sometimes though, even for those who I know very well, I sometimes feel as though I've excluded myself without intending to do so. For example, if there's a conversation that ties in with some basic biology or psychology, then I'll use analyze whatever is being said, use complex terminology that my professors and most classmates know because that's the environment I'm used to using them in. Take for example, someone mentions something about laughing and in response you mention fMRIs, nucleus accumbens and so forth. It kills the mood pretty fast unless the people understand those and other more complex concepts and terms.