Hello Lady Macabeth!
There can not be a rule of thumb in this regard. Sometimes you need a continuous interaction to keep the the relation strong, something like watering a plant daily, where as some relationships are evergreen.
But friendship is a pretty different situation altogether. I personally feel (and I havemy own experience and track record) that friends usually do not get agitated by greater frequency of interactions. That is the only difference in marriage and friendship

. When you are really good friends you usually tell each other to get off if you want a quiet moment, so there is nothing much formal.
Well I have a very selective circle of friends, and I myself think of the same think not to be bothering or imposing mself on them. So I often simply ask them if they want me to leave or go away and if they say it is okay then it is after all their choice and I take the liability of my mind.
I hope this would help you. The best of luck for the relationship!!!
Regards
ZILCH HOUR