Hubby took a small dose of Seroquel for about a year. He took it right before he went to bed and once he got up in the morning he seemed to be ok. If you're not taking it at night, I would see about switching. If you are, then you may need to talk to your doc again. Everyone reacts differently to every medicine. My friend works with someone who takes 12 times what my hubby took and it doesn't make her sleepy at all.