I gained 30 kg and my legs were in pain all the time while on zyprex I would only take it again if my life depended on it and I was in bed with depression and already on a very high does of anti d's like when they put me on about a year ago.....I'm now fighting to stay better so dont need zyprxa again. but it really does work in my oppinion but it should be taken as last attemp to gain your life back. I'm glad I'm out of bed and dealing with life again I thank zyprexa but I sure dont want to have to use it time soon again.