I have ben on a lot of meds that helped one of my probles (dysphoric manias) a bit and my depression only enough hto keep my nose above water. It was only recently that my meds have left me feeling normal enough to function. It is very individual and I suspect that not all depressions have the same origin biochemically. I sympathize greatly and can only add that as Rohag says, don't be intimidated into being quiet about how you feel. The pdoc needs YOU to tell him or her. They can't tell otherwise.
HHHHHHHUUUUUUGGGGGGSSSSSS!!!!! and good luck.