How familiar are you with down syndrom children? A lot of what you discribed as having trouble with is just slowing down with her. Sometimes they can only process one thing at a time (i.e. get confused when asked more than one question at a time). They are acutely aware of and pick up on other's moods with surprising accuracy. So if she says she thinks you mad and you say you are not when you actually are, she will know, she will not trust. They are also aware of their lack of fine motor skills so knocking over the drink is common, it's all in how you handle your reaction. If you would like, I can put together a short fact sheet that may help you work with her. Would that help?