Seroquel XR has been a blessing once I got over the drugged feeling. I take it about a half hour before or after I eat dinner and it does a wonderful job keeping my mood even. The drugged feeling has gone now yet the sleep pattern hasn't changed. I still wake up at approx. 3am and then am up and down the rest of those early morning hours. I do take sleeping pills otherwise I wouldn't sleep at all...I am just glad that I am starting to feel like myself again.