I haven't taken Depakote, but I do take Prozac. My p-doc took me off it for a short time and tried Celexa, but I started to go down into the pit again. Prozac keeps me out of the deep, dark pit. It's not perfect, but it is better than how I was before I went on an anti depressant. It's important to use a mood stabilizer as well.

I have heard that Depakote is a good mood stabilizer.