After the series of tests, was your brother treated for any of the physical conditions you refer to? Does he continue to receive treatment for any of the conditions? Has he been told by a physician all or some of his physical symptoms are psychosomatic?

My point in asking these questions is with respect to getting a physical. If your brother currently is being treated for the physical problems, the question becomes his prognosis for recovery. If the treatment is not progressing well, are there other treatment modalities that should be considered.

If your brother has been told his physical conditions are psychosomatic, perhaps another physical to get a second opinion might be a viable option.

Were the anxiety meds prescribed by a treating physician or a psychiatrist? I wonder too if your brother thinks the doctor(s) he is seeing also think the physical conditions are all in his head? Perhaps the impetus for therapy could come from a referral by a treating physician as a helpful adjunct to the current treatment?

Your brother needs to have confirmed that you and the rest of the family are not his enemies, that you believe something serious is going on and that you would like to offer your assistance in helping him through the tough time he is experiencing. One thought is to remind him that the treatment he received ten years ago helped him to get back on track.

In the end, all you can do is to offer to help. If your brother refuses your offer, you might tell him if he changes his mind the offer still stands. In the interim, phone calls and emails to remind him you care and hope he is doing better would be useful.

Good luck.