I take Pristique so I shouldn't comment but I was interested to see what Lexipro was, and just by looking at the side affects I would say no, I would never try it. I was interested because I have anxiety and depression, but I take Klonopin and Pristique in the morning and it has seemed to restore me to a normal functioning rate, but I wish I had more energy, but that is probably because of schizophrenia and a-typical anti-psychotics. I might actually take a higher dosage of Pristique because this is my worst time of year, and I am pretty depressed. It is a new anti-depressant and one thing that it doesn't cause for males is sexual dysfunction so that is my main complaint about some of the anti-depressants. I know it doesn't cause hormonal imbalances to not be able to have sex but it depresses me just to think about it.