So this year is the longest I've been on Seroquel [XR] and I've also gotten sick more times than I ever have in the past... does the use of antipsychotics/Seroquel reduce the immune system? I know Clozaril for sure does, but didnt know about Seroquel...[/quote]

Ive noticed a definite decrease in sickness after starting meds for bipolar. i was in to see the doc for colds,flue, ear infections and all around feeling crappy all the time. i think the high level of stress from the undiagnosed bipolar killed my immune system.