Hi you guys, I'm new on the site. Your posts have got me thinking. I am on a massive dose of Seroquel - 800mg - yes that's right! But I do need to be on that much and no, I have no sleepiness during the day after taking as a night time med. I am on several other high octane meds. I have Bipolar as well as panic and anxiety Disorders and I have experienced what you guys have described with terrible panic attacks, often coming straight out of sleep into a fully blown panic attack and a horrifying nightmare in between with horrific auditory halleucinations - and I am frozen stiff so much that I can't even move a finger for fear of the man or the people in the house (all delusional) coming to get me if I move an inch. I wonder could the Seroquel actually be contributing to this? Mind you I have had this scenario for years (infrequently thank God), many years before I started on psych meds, so it's hard to know if it's the illnessess or the medication. Dam. lol