I've been on a lot of different meds. Then they decided I had bipolar, so now I'm on lithium and cymbalta. It was working well for a long time. Then I told my pdoc that I thought the lithium made me gain weight and could we please cut down the dose. So we did, in half. I'm losing weight, but not sure if it is because I started a weight loss program or because of the cutting lithium down. Now I find myself in deeper depressions more often and I just feel YUCK. I feel tired, yet not like I could sleep. I want to lie down in bed a lot, but I have to work. I want to sleep, but I just don't feel that tired. I wake up every day around 3 or 4 a.m. wide awake. Isn't there a drug or something that will just make the bad feeling go away?