I have completely lost my libido as well and also have trouble reaching orgasm (I'm at 20 mg) but also had the same trouble at 10. I am also finding though that it's not really helping with my depression, so it may not be the right med for me for many reasons. I've been on it now for 5 months and initially I started to get better but relapsed about 2 months ago. I am seeing a new doc this weekend so fingers crossed...otherwise, no real side effects.