You can't diagnose what is wrong with your loved one. There are numerous mental and/or physical illnesses that could be causing these symptoms. As far as the spouse who doesn't seem to want to acknowledge the problem: seeing someone you love change so drastically is scary. Many people do not know what to do. Many people cannot admit there is a problem because they themselves feel responsible. At this point you best course of action in to contact the Mental Health Department of the State this person lives in and ask tem for assistence. Again, only a professional in an appropriate setting can make a diagnosis.