I'm looking to pick your collective brains if I may. I have been feeling better the last couple of months and it has felt that the depression is finally lifting. But this last week I've been more on edge, feeling agitated and just not so great. A couple of times I have thought I've heard some music that hasn't been there, but that hasn't bothered me too much - it's been a pretty fleeting sensation. But a couple of times this week I have woken very soon after falling asleep, and have been very disorientated, I find it hard to move physically and to work out what's going on. The first time, I thought my daughter was there and I spoke to her before I realised there was no-one there. Last night, I can't quite put my finger on what I thought was happening, but I was scared, my heart was pounding. Reminds me of a recurrent nightmare when I was a child - where the bed would get bigger and bigger, and I would get smaller and smaller, and less able to move - I know, that doesn't sound very frightening, does it? - but for some reason it was pretty scary.

So - does anyone have any ideas about this? It feels quite dream-like - and the fact that I can't quite remember it clearly seems to support that - but it also feels that I am awake. It reminds me a little of depersonalisation, which has happened a few times when I was very low, but not very often and not for a long time now.

I have been reducing one of my meds over the last few months, and have gone from 200mg amitriptyline to 50mg; at the same time, I have introduced bupropion (wellbutrin) and am taking 450mg. I do wonder whether, having reduced the sedating AD, the dose of bupropion is now too high and is contributing to some odd things happening.

If anyone has any ideas or experiences to share, that would be great. Thanks.