I take a 25mg tablet in the morning, another 25mg tablet in the afternoon and then another 300mg tablet right before bed. Honestly, when I first started taking this medicine I hated it, because it would make me sooooo sleepy. But now that I am more used to it I don't mind it at all. It does help me tremendously. I was prescribed Seroquel for the same reasons as you...anxiety and stress. I hope it works out for you. Everyone is different when it comes to medication. Best of luck.

-Jennifer-