PTE - 37.5mg three times daily is not a high dose for treating depression "for most people"; still, many find relief at 75mg per day (Everyone is different!!!) You are taking a total of 112.5mg of Effexor (venlafaxine) daily. I find that a normal antidepressant dose "for most people" is 150mg per day.

NOTE: Be sure to run the dosage increase past your doctor first before just increasing it yourself. There may be a reason for your low dose (ie. doses to treat anxiety are usually 37.5mg to 112.5mg) and you should check this out with your doc.

Hope that this is some help. - Cam