I take topamax, I have been for almost a year, yes 50% of patients who take it lose on average of 18lbs. It is not only a mood stabalizing drug but it has anitdeprassant effects. The drugs for me is fine. No side effects except in winter. I lost close to 25 lbs on it so I'm above the norm I was on Valproic Acid prior to Topamax so I know what it is like. Good luck
Adam