I was on Topamax for about 2 months for migraines. It made me constantly sick to my stomach....I would even have dry heaves after not eating. My neurologist told me that one of the more beneficial side effects was weight loss....but I got to the point where I would be in the middle of a conversation and just start gagging. I did lose weight though! LOL!! Didn't stay on it long enough to really have an impact on the migraines though.