Be REALLY careful with Topamax. Were you weaned on to it or did you go straight to 100mg? If you did, that's shocking and I would be a bit concerned about your doctor. You shouldn't ever start taking it at a dose that high. Topamax is a VERY VERY VERY strong drug and while weight loss MAY happen, it is not a guarantee. I have been on Topamax for about a year to control my migraines. I started out with 12.5 mg per day and worked my way up over many months to a dose of 200 mg/day.

Yes, it does feel like you've lost part of your brain at times, and no, that doesn't ever go away completely. I take 100mg morning and night and even now, I forget simple words and my short term memory is crap. But my migraines are almost gone and for me, the trade off is totally worth it.

But...you also need to know that I haven't lost one itty bitty pound. In fact, I have GAINED 7. (I also take Cymbalta, which is also known for weight loss so maybe I'm just a freak?!?)

And yes, it does change the way things taste (in particular, diet soda) but you get used to it after a while.

Good luck and please, please be careful.

Feddy