I've isolated for many years as well, so I know how you feel. Are you seeing a pdoc or a T? If you are still having a lot of depression, maybe you can ask about a med adjustment?
Anyhow, welcome to PC. There are a lot of great people here who understand!!
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From the movie The Hours: "If I were thinking clearly, Leonard, I would tell you that I wrestle alone in the dark, in the deep dark, and that only I can know. Only I can understand my condition. You live with the threat, you tell me you live with the threat of my extinction. Leonard, I live with it too."