I work in healthcare and I see people every day that tweak their meds, omit certian details and even say that they're taking things when they really aren't. My personal philosophy is that first and foremost you have agreed to be cared for by this doctor and you should make every attempt possible to follow the plan of care (within reason--I DO NOT beleive in blindly following someone's advice simply bc they're a doc). If you feel a change needs to be made don't leave your doc out of the loop. Talk to him/her about it and weigh out the pros and cons together.
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