Hah, yes I believe Seroquel will do this to you. I have been on it for depression, and ironically, sleep problems.

It was prescribed to take 1 tablet before bedtime. Took it, and after about 10 minutes of laying bed, I would then wake up the next morning, ready to start the day.

But it made me feel very crappy during the day, like I wasn't "there". It made me tired, grumpy, and frustrated at the silliest things. I quit taking it, and I didn't care what my doctor said, it wasn't helping, it was only making my depression feel deeper and lost.