I think Anne Frank took Valerian.

aha! Yes she did...

http://history1900s.about.com/od/ann...5AnneFrank.htm

5. Depression Medicine
Those around Anne Frank saw her as a bubbly, vivacious, talkative, perky, funny girl and yet as her time in the Annexe lengthened, she became sullen, self-reproachful, and morose.
The same girl who could write so beautifully about birthday poems, girl friends, and royal genealogical charts, was the same one who described feelings of complete misery. On October 29, 1943, Anne wrote, "Outside, you don't hear a single bird, and a deathly, oppressive silence hangs over the house and clings to me as if it were going to drag me into the deepest regions of the underworld.... I wander from room to room, climb up and down the stairs and feel like a songbird whose wings have been ripped off and who keeps hurling itself against the bars of its dark cage."
Anne had become depressed. On September 16, 1943, Anne admitted that she has started taking drops of valerian for her anxiety and depression. The following month, Anne was still depressed and had lost her appetite. Anne says that her family has been "plying me with dextrose, cod-liver oil, brewer's yeast and calcium."
Unfortunately, the real cure for Anne's depression was to be freed from her confinement - a treatment that was impossible to procure.