According to my doctor BP patients go off their meds twice on average...
I'm above average and every time it was a bad idea
I agree with gravyyy, if you're going to try, do it after you're stable for a while.

If you are having trouble with a particular drug, see if you can swap it for a different one - different things work for different people.

Also - switching meds without talking to your doctor can also be a REALLY bad idea