Hi I think everyone who replied has a peice that is correct. Rapid cycling can physically change the size of the brain. And rapid cycling can originate from medications themselves. The life cycle of bipoalr is known to also be different in everyone with increased cycling and severity of the symptons.

The creativity felt in mania or hypomania can be missing because of the cycling and the mood especially depressive it settles in as well as the medication effects it has on everyone.