I isolate myself a lot & find that it makes me almost agoraphobic--in that if I spend 5 days at home alone (when husband is on a business trip) I'll start to not even get the mail until it is dark out.

Then I had to go to my therapist & I was so anxious that I couldn't recognize familiar streets. I realized as part of my "treatment" I need to make an effort to get around people even if it is just going to a coffee shop w/a book. I also have a very hard time being w/people one-on-one as I feel socially inept, but if I take a class (tennis, knitting, computer, exercise, etc.) then I can be around people & have a focus so I can talk about my dropped stitches or my lousy overhead instead of being put on the spot where I have to reveal "me."