Getting meds right is horrible. Everytime I get frustrated and think that life will never be better, my doc reminds me of that we will be able to find meds that give me a good life. But I sympathise with your frustration and suffering.
I understand the feeling of the nurses getting sick of you, at first when you get sick everyone is happy to help, but when it goes on and on, I worry about being a burden and of them not wanting to hear the same problems over and over...
How did I deal with it - sometimes not very well, (poor med complience!!!). In the end it is just perserverence. One other thing that really helped me was therapy, working out how what I thought and how I responded to situations was affecting my mood and learning how to change that. It means the meds have less work to do coz there is less mood to balance
Thinking of you, we are all here for you.