I think most of us have gone off some or all of our meds at some point. This past spring I felt overmedicated and went from taking 6 meds to only 2 (one of which was not psychiatric). I had a good brief period of my head feeling clear and my mood improving, then bam, I became anxious and depressed. So I had to go back on a couple more meds and had a few changes made by the p-doc. Finally she found me an anti-depressant that actually works. Now I'm in good shape. By the way, she was kind of mad I went off most of my meds without her input, but she stayed on as my Dr. because she saw how much better I was feeling initially. So, I think in your quest to feel better, you can definitely test to see what's really working for you...titrate off slowly and then add back in what's helping and eliminate what's not. I'm not a Dr. so don't take my advice without talking to a p-doc (not necessarily your old one since he doesn't listen). I'm just saying what I did worked for me because we eventually found something that helped because of my dissatisfaction. Just putting up with a combo that isn't working will get you no where. And I'm sure your new p-doc will help you to find a new combo. Things will get better.