I'm not an old hat at this though I have been depressive for a few years now. On antidepressants and have elevations of the meds occasionally . Now I'm told Bipolar is my attachment though symptoms are all there is to go on .I'm learning what I can on my own when I can focus and find life is waiting in front of the TV and feeling alone. Meds for certain parts of the brain functions are hit and miss . My only way to get by seems to shut down everything that I did or thought about doing as to not be more depressed . I have the 'luxury' of my kids are grown and the 'spouse ' is financial support . But ALONE is a big down ...I find the sleep a big desire ...if not for my cats and dogs being my daily responsibility . I do take new meds as of recent as in pristiq and seroquel XR and I'm in the holding pattern ...waiting . Deplin is one I 've taken for a while now and I still feel down . Usually by this point I've erased my post...have many times . I've stopped trying to have a 'life' so I don't feel the stress of the work of doing so. I just miss enjoying life even if I'm alone doing it .