They affect me very differently as well. Klonopin, like Phrick said, has a super long half life. So if I take this even just once a night, after a week or so, I start feeling depressed and crying often. However, it IS the one thing I can take when I'm in a social/party situation and feel panic-attack-y or overwhelmed. So I guess for me, it's the go-to for social anxiety.