I have had GERD since was little and use Protonix for years, which is fortunately still working. The new Gast/ENT doc asked more about my hayfever allergies after telling him about the frequent trips to the bathroom; he sent me for allergy testing. Turns out I have food allergies too, more like intolerances, that cause irritable bowel syndrome. I cut out those foods or minimized them, world changed. Didn't affect the GERD unfortunately, but feel better and no more frequent trips to the loo.