I don't like that I am putting on weight with Seroquel, but every time I stopped it I would get borderline psychosis symptoms. I had to put two and two together to come up with that, because I was prescribed Seroquel at 25mg for sleep as needed. When I was sleeping well, I went off it and then would start in with my paranoia and delusions. I am now up to 100mg per night and in conjunction with my other meds, I have been balanced for the first time in so long. Of course, this has only been for a few days, but I'll gladly take it. Now, if I can just do something about the weight...