I take Topamax for seizure control and as a mood stabilizer on top of Lithium and I have to say that I wouldn't be able to be in as much control that I'm in without these two medications. I notice that I'm not depressed with these medications but I do notice (but I think this is just the nature of my illness right now) that I'm hypomanic.

Topamax didn't make me depressed, nor did it cause other mood problems, which is good because this was a first choice for me when I had my first seizure.

Remember that Topamax is not a first choice for bipolar depression.

Hope this helps and best of luck,
Andy.