Thank you very much every one. As you have all pointed out it is very difficult because it not what she says particularly, more how she says it. She just gets my back up and it is difficult not to react to her. However I am not the only person she has pipped off. She is so aggressive, but in a very underhand way. I am going to take the advise on here and try very hard not to get into dialogue with her. I will also attempt not to sit next to her. It is possible to desk hop and I could probably do it with out it being too obvious. She spreads poison where ever she goes. I don't love my job as much as I used to because of her nastiness. I am trying hard to think in a mindful way. I will ignore her.