I went through 31 TMS treatments, driving over 60 miles every Monday through Friday, and I had very little improvement. The Pdoc who did it said I was a success because my scores of depression slightly impoved. In other words, instead of thinking about killing myself daily, I think about it 5-6 times a week, or instead of feeling guilty everyday, I feel guilty 5-6 days a week and other such depressive symtoms with little improvement in my scores. I went for TMS thinking this would end my depression, even though there was no guarantee. Now I feel even worse knowing that my husband spent over 8,000 dollars, and I once again failed to make improvements in my long term depressive state! I've been on numerous types of mood stabilizers & anti-depressents, and my regular Pdoc has all but given up on me, saying that I'm treatment resistant. In Jan., I'm going to the Pdoc who did my TMS because at least he switched my previous meds to new meds, and he found that I had low thyroid levels and started me on thyroid medicine about 2 weeks ago. How long should I expect to see an improvement with my new meds that I've been on for about 2 weeks-- Wellbutrin CR 150, Nuvigil 150, and Symbyax 12-25, and Levothyroxide? For almost a year I've been taking Klonapin 1mg and Dioxipine 150 to help me sleep at night. What Can I do next? I'm very afraid of ECT!!!