Tracy, as one who has been on a few different meds, I've found out that the human body, naturally, has to adjust to either a new drug or a new dosage. It would not be normal for the body to not have some responses to said changes. Did you have a big increase in dosage? And how long have you been on Effexor? I was on Effexor and probably can help you with this. xoxoxo pat PM me...I'll come home for lunch.