SSRI'S have been shown to help tremendously with PMDD-prozac,zoloft,paxil,celexa.
sorry if i don't write more about it i'm not feeling that well tonite. people with PMDD may have abnormal reactions to hormone changes that occur each cycle. and may change the estrogen and progesterone levels that normally occur with menst. causing serotonin deficiency. thus the whole possibly trying the SSRI medication might help route. just a theory nothings proven.