There is a book about alcoholism that is really good. I can't recall the name right now and I tried to find it on ebay but can't find it. I'll keep looking.

You are right that in end stage liver disease there is 'reverse tolerance' if that is what you want to call it. By then the liver is too damaged to repair itself and can no longer process alcohol and alcohol has stronger effect.

I will PM you the title of the book when I find it.