There can be that effect and it is great you are going for a referral for a second opinion. I saw your other post first, didn't know you'd decided to go. It should help and get you some answers you need from an unbiased opinion.

It's not easy getting started on new meds and combos of meds, which one is causing what but you just know, it isn't doing what you expected. So frustrating. Keep a list of your history and symptoms to take to the new doc and medication dosages, less to fill out when you get there. I wish you the best for your appointment and will hope for some relief soon.