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I think it really depends on the condition.
There are some disorders that you really can't change. Disorders that have a very physical cause in the brain. Personality disorders, schizophrenia, etc. however those who suffer from mental health issues unrelated to their brain health probably can under most if not all circumstances: what varies is the level of work put in. It's understandable that some people would claim that they can't change when the effort to change themselves outweighs the amount of time and energy they have.
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