I have had a life without close friends. At abot 50 yrs I got a few, and now medication seems to help.
Why?
I had problems i primary scool, and social pressure later on tended to make me push onto others. With no appearent response (werw they owerwhwlmed?), I found someone else.
Shifty, hyperactive, socially clumsy and short sighted - probably. I did not feel included in social groups either, despite trying to join.

All right, I thrive in my own company, running about. Now, at last, I have experienced lasting friendships